The two have been missing since around 8 am.
Two Indian High Commission officials are missing in Islamabad, news agency ANI reported on Monday quoting sources. The two have been missing since around 8 am.
New Delhi has complained to the Pakistan government.
The incident comes after two Pakistani officials at the Pakistani High Commission in New Delhi were accused of espionage and deported. The two worked in the visa section in Delhi.
Several top Indian diplomats in Pakistan have been aggressively tailed in Islamabad over the last several days and India has even protested against the excessive surveillance.
The vehicle of India's Charge d'affaires Gaurav Ahluwalia was chased by Inter-Services Intelligence (ISI) member recently. A biker was seen following the official's car.
In March, the Indian High Commission in Pakistan sent a strong protest note to the foreign ministry in Islamabad protesting against the harassment of its officers and staff.
In the note, India cited 13 instances just in March and asked Pakistan to put an end to such incidents and "investigate these incidents urgently and instruct the relevant agencies to ensure that similar incidents do not recur," according to ANI.