The Simpsons is ending the use of white actors to voice black and ethnic minority characters, producers have said.
The move follows years of controversy about the issue and calls for greater diversity within the entertainment industry.
It also comes against a backdrop of heightened tensions in the US about racism, following mass protests over the killing of black Americans by police, sparked by the death of George Floyd.
Image: Hank Azaria confirmed in January he would no longer perform the role of Apu
In a statement, the Fox network, which broadcasts the show, said: "Moving forward, The Simpsons will no longer have white actors voice non-white characters."
The Simpsons, which has been on the air since 1989 and is syndicated in more than 100 countries, had faced public pressure for years over for having Hank Azaria, who is white, voicing Indian shopkeeper Apu.
Azaria said in January he would no longer perform the role, which had been criticised for reinforcing racial stereotypes.
He has also voiced the Simpsons characters of black police officer Lou and the Mexican-American Bumblebee Man.
It’s been an honor to play Cleveland on Family Guy for 20 years. I love this character, but persons of color should play characters of color. Therefore, I will be stepping down from the role. pic.twitter.com/FmKasWITKT— Mike Henry (@mikehenrybro) June 26, 2020
Another white actor - Harry Shearer - voiced the character of Dr Hibbert, who is black.
The Simpsons announcement followed similar steps by another popular animated show.
Mike Henry, a white actor, who had lent his voice to Family Guy character Cleveland Brown since 1999, said on Twitter he was stepping down.
He said: "It's been an honour to play Cleveland on Family Guy for 20 years. I love this character, but persons of colour should play characters of colour. Therefore, I will be stepping down from the role."
Earlier this week Frozen star Kristen Bell revealed she too would no longer be lending her voice to a non-white character in Apple TV+ comedy Central Park.
In a statement on Instagram, Bell said her playing Molly, a mixed-race character, "shows a lack of awareness of my pervasive privilege".
And actress Jenny Slate announced she will no longer voice a black character in the animated series Big Mouth, saying her taking the role was "engaging in an act of erasure of black people".